GW-501516 Dosing Protocol: Cardarine PPAR Guide
Also known as: Cardarine, Endurobol, GSK-516
What is a Peptide?
A short chain of amino acids (2-50) linked by peptide bonds. Smaller than proteins. Your body produces thousands of peptides naturally as signaling molecules that regulate everything from appetite to healing. Therapeutic peptides mimic or enhance these natural signals.
Research reference only. GW-501516 is not FDA approved for human use (unless specified above). This information does not constitute medical advice.
Overview
GW-501516 is a PPARδ agonist originally developed for metabolic and cardiovascular diseases. It dramatically increases endurance by shifting muscle metabolism toward fatty acid oxidation. Note: This is technically not a peptide but a PPAR agonist compound.
Mechanisms of Action
- Potent and selective PPARδ agonist (EC50 = 1.2 nM)
- Increases fatty acid oxidation in skeletal muscle
- Preserves glucose for brain and other tissues
- Upregulates SIRT1 via Sp1 activation
Research Protocols
Summaries of published research. For educational purposes only.
| Protocol Name | Source | Dose | Frequency | Duration | Route | Evidence | Link | Save |
|---|---|---|---|---|---|---|---|---|
| Endurance Enhancement Protocol | animal study | 10-20 mg | Daily | 8-12 weeks | Oral | animal | Sign in to Save |
Community Outcomes
Community Data Coming Soon
Aggregate community outcomes will be displayed here once we have more reports. Be one of the first to share your experience!
Outcomes are self-reported and unverified. They represent individual experiences and may not reflect typical results.
Important Warnings
- •Development halted due to cancer in rodent studies
- •Not approved for human use by any regulatory agency
- •May cause liver toxicity
- •Long-term safety unknown
Where to Get GW-501516
Licensed Compounding Pharmacy
Requires a prescription from a licensed provider. Compounding pharmacies can prepare custom formulations of GW-501516 tailored to your prescribed dose.
Find a ProviderTelehealth Consultation
Get evaluated by a licensed physician online. Many telehealth providers specialize in peptide therapy and can prescribe GW-501516 if clinically appropriate.
Get a ConsultationThis page contains affiliate links to licensed providers. We may earn a commission at no cost to you. Learn more
Avoid unlicensed vendors. We only link to licensed, regulated providers. Never purchase peptides from "research chemical" vendors or unlicensed sources. These products may be contaminated, mislabeled, or illegal.
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