EDUCATIONAL AND RESEARCH REFERENCE ONLY — NOT MEDICAL ADVICE — NOT FDA APPROVED

MOTS-c Dosing Protocol: Metabolic Research Guide

Also known as: Mitochondrial Open Reading Frame of the 12S rRNA-c

metabolic

Research Reference Only

This information is for educational purposes only. MOTS-c is not FDA approved for human use. The protocols listed are summaries of published research studies and do not constitute medical advice. Always consult a licensed healthcare provider.

Overview

MOTS-c is a mitochondrial-derived peptide encoded by mitochondrial DNA. Research has investigated its role in metabolic regulation, insulin sensitivity, and exercise adaptation.

Mechanisms of Action

Activates AMPK pathway
Improves insulin sensitivity
Enhances fatty acid oxidation
Regulates mitochondrial function

Research Protocols

The following protocols are summaries of published research studies. They are presented for educational purposes only and do not constitute medical advice.

Protocol NameSourceDoseFrequencyDurationRouteEvidenceLink
Metabolic Study
animal study
0.5 mg/kgDaily14 daysIntraperitonealanimal

Important Warnings

Safety Considerations

  • Limited human research
  • Exercise mimetic effects under investigation